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Alternate Names CD8A,  MAL,  T-cell surface glycoprotein CD8 alpha chain,  T-lymphocyte differentiation antigen T8/Leu-2
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Background CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Abbre CD8a
Swissprot
Host Rat
Reactivity Mouse
Clonality Monoclonal
Isotype Rat IgG2a, κ
Isotype Control PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Applications
FCM
Cellular Localization
Membrane
Form Liquid
Concentration
0.2 mg/mL
Conjugation PerCP/Cyanine 5.5
Conjugation Information PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Storage This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date 24 months
Shipping Ice bag
Product Recommendations for Literature Synchronization

Note: Data for this module come from published literature that cites this product, displaying other products used together in the same research paper.

Associated Targets

Searching publications using CD8a as the keyword shows that the gene above is closely associated with CD8a in research. Results are sorted in descending order of research relevance. (The displayed numbers represent the number of publications in which both terms co-occur.)

Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Cat.No. Product Name Clone No.
AN00331UJ PerCP/Cyanine5.5 Anti-Mouse CD8a Antibody[YTS 105.18] YTS 105.18
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